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Crossing Smad9tm1Mwst with Tg(EIIa-cre)C5379Lmgd mice resulted in the removal of exon 3 and the neo cassette. RT-PCR demonstrated the complete deletion of exon 3 in mutants. The deletion putatively results in the deletion of part of the linker and one-third of the MH2 domain of Smad9. (J:99098)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
