LacZ cDNA followed by a floxed neo selection cassette was inserted into the start codon in the first exon. RFLP analysis and absence of transcript confirmed successful targeting of the locus. (J:98806)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count