Log In|Sign Up
EN
ES cells containing Cbfbtm1Ppl were targeted a second time to insert a floxed cassette encompassing exons 5 and 6, as well as the bovine growth hormone polyA signal and a PGK-hygro cassette into the Msc1 site in intron 4. This design allows the wild-type Cbfb transcript to be expressed. Cre expression would remove the cassette and restore expression of the knockin allele. (J:105040)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
