Exon 12, which encodes part of the extracellular domain and is common to all isoforms, was disrupted by the insertion of a neomycin resistance gene. Flow cytometry of splenocytes, lymphocytes, lymph node and bone marrow cells with an antibody recognizing all isoforms failed to detect protein on any cells. (J:57681)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count