A targeting vector was designed to flank exon 1 with loxP sites. Transient transfection of cre recombinase excised a floxed neo inserted into intron 1. (J:98195)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count