Exons 20 and 21, which contain the RNaseII domain, were flanked with loxP sites. A neo with a 5' loxP site was included in the targeting vector and was inserted into intron 19. (J:98192)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count