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A targeting vector was designed with a GFP fused to the ATG in exon 2 by a 5-amino acid linker, GGSGG. A PGK neo was included in intron 2 and was subsequently removed by crossing with Tg(EIIa-cre)C5379Lmgd mice. Western blot of heterozygotes demonstrated that expression of the GFP-GR fusion protein is equal to that of the endogenous protein. (J:98328)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
