A loxP sequence and an Flp-flanked neo was inserted 381 bp upstream of exon 12 and a second loxP sequence was inserted downstream of exon 12. Exon 12 encodes the putative transmembrane segment M3. Crossing with Tg(EIF1A-flp)66Mim removed the neo. Western blot analysis demonstrated that protein expression in cerebellar homogenates from mutants was comparable to that of wild-type. (J:97405)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Insertion
--
1
1
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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