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A targeting vector was created to introduce a stop codon at amino acid 150. A neomycin resistance cassette was also included in the vector for selection purposes. Absence of transcript was confirmed by RT-PCR of total RNA from mutants. Flow cytometry further showed absence of protein on the surface of stimulated mutant splenocytes. (J:59204)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
