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The Jun oncogene cDNA was inserted into the L7deltaAUG vector, which is a PCR-mutated Purkinje cell protein 2 gene. The vector comprises the entire genomic sequence of Pcp2, including 1 kilobase of 5'-flanking sequence and about 200 bp of 3'-flanking sequence, modified to eliminate a BamHI restriction site in the third intron and all potential transcription start sites. The cDNA was inserted into the only remaining BamHI site, in exon 4, so transcription occurs from the Pcp2 promoter and translation from the initiation site of the cDNA. (J:96313, J:96314)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
