The trap vector, pU-Hachi, was inserted into the fifth intron of the gene, resulting in the deletion of 634 bp of genomic sequences. Northern blot and RT-PCR shows the complete loss of the wild-type message that is replaced by the transcription of a fusion message. (J:96209)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count