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An insertion of the Omnibank Vector VICTR24 in the first exon of the gene led to the splicing of the endogenous upstream exons into the gene trap cassette. This resulted in the production of a fusion transcript that contained the beta-galactosidase gene. Western blot analyses demonstrated absence of encoded protein in homozygous mutant mice. (J:264021)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
