The retroviral gene trap vector VICTR24 integrated between exons 3 and 4 of the gene locus. This vector contains a splice acceptor sequence followed by a neomycin selection cassette, and a BTK gene. Gene inactivation was confirmed by immunoblotting of limb muscle homogenates prepared from homozyogtes. Immunoblotting also confirmed that there was no compensatory increase in expression of the Casq2 gene. (J:140828)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S5/SvEvBrd
Gene trapped
Insertion of gene trap vector
--
1
2
13

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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