A gene trap vector consisting of LTR sites flanking a Beta-geo cassette containing a splice acceptor and a PGK-puromycin resistance cassette containing a splice donor integrated into intron 1. No mRNA was found in the liver of homozygotes when analyzed by RT-PCR. Western blot confirmed lack of protein. (J:82747)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S5/SvEvBrd
Gene trapped
Insertion of gene trap vector
--
1
--
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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