This transgene contains the muscle creatine kinase promoter and cDNA encoding the N-terminal 712 amino acids of Mkl1, without the transcription activation domain. Two lines were generated that had the same overall phenotype with varying severity. Line 1 had approximately 4-fold higher expression and a more severe phenotype compared to line 2. This is a representaive record for both lines. (J:96122)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count