The transgene contains wild-type human alpha synuclein cDNA and the mouse prion protein (Prnp) gene promoter together with its 5' untranslated region (UTR) containing an intron, and its 3' untranslated sequences. Transgene expression was detected in the cerebral cortex, spinal cord, and cerebellum. (J:76657)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x C3H
--
Insertion
--
1
--
13

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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