A beta-geo cassette which includes a splice acceptor site sequence, a bacterial beta-galactosidase maker (lacZ), an internal ribosome entry site (IRES) and a neomycin resistance sequence, replaced exons 2 and 3. This results in the expression of an aberrant transcript encoding only exon 1 spliced to a beta-geo. (J:239386)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count