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An IRES-lacZ gene replaced exons 2, 3, and 4. In situ analysis confirmed the absence of endogenous protein in the testis. RT-PCR showed a very low level of transcript expression in the testis that is likely due to read through of the IRES-lacZ cassette. This mutant transcript cannot produce functional protein due to frameshift mutations. (J:88649)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
