Coding exon 1 was targeted. A 72 bp genomic fragment starting with the ATG start codon in exon 1 was replaced with an IRES lacZ/MC1neo selection cassette. Transcript is absent in homozygous mice and protein was shown to be absent by Western blot analysis. (J:103485, J:174414)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S5/SvEvBrd
Targeted
Insertion, Intragenic deletion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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