The transgene contains 4.8 kb of rat tyrosine hydroxylase (Thy1) promoter sequence, a human alpha synuclein (SNCA) cDNA sequence carrying a G209A transition mutation, which encodes an Ala53Thr amino acid substitution, and an SV40 polyadenylation sequence. (J:70209)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Swiss Webster x (C57BL/6 x DBA)F1
--
Insertion
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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