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A 1.8 kb fragment containing a mutant human TP53 with an arginine to histidine mutation at codon 273 was cloned into the EcoRI site of the rabbit Beta-globin exon 3 and placed under the transcriptional control of the human Surfactant associated protein C (SFTPC) promoter. ~7 copies of the transgene were incorporated into the genome. (J:80317)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
