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This transgene expresses the P230 variant of the human derived BCR/ABL fusion protein, involving BCR exon 19 fused to ABL exon 2. This gene was cloned downstream of the LTR from the Murine Stem Cell Virus (MSCV), which was referred to in the original reference as PCMV. Mice carrying this allele had 5 copies of the transgene incorporated in their genome. (J:84626)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
