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A neomycin resistance gene replaced exons 2-4. RT-PCR showed that transcripts from mutant animals lacked these exons, and that exon 1 was ligated to exon 5. A stop codon was created by frame shifting in the resulting truncated mRNA transcribed from the direct connection of exon 1 to exon 5, and would result in a 14 amino acid peptide, if any. (J:95518)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
