Exon 2 was flanked by loxP site and a frt-flanked neo cassette was inserted downstream of exon 2. The neo cassette was removed by Flp-mediated recombination. (J:126581)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count