An 11 kb fragment of the Nr0b1 regulatory region drives expression of 5kb of murine Sry genomic DNA. Two lines were generated which showed partial (line 8) or complete (line 23) penetrance of sex reversal. Line 23 was selected for further study. (J:45884)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count