A targeting construct was designed to insert loxP sites into introns 1 and 2 to flank exon 2. An FRT-flanked neo was inserted upstream of the intron 2 loxP site. This allele is hypomorphic. (J:100575)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count