A loxP site was inserted upstream of the coding region and an FRT site flanked neo cassette with a 3' loxP site was inserted downstream of the coding region. Germ-line flp-mediated recombination removed the neo cassette, leaving the coding region floxed. (J:155058)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count