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EN
Expression of a signal resistant mutant form of Hdac4 in which serines 246, 467, and 632 were replaced with alanines was driven by the a 3 kb fragment of the Col2a1 promoter and the Col2a1 3 kb chondrocyte-specific enhancer region. Expression of the transgene was seen in proliferating chondrocytes. (J:94631)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
