A sequence from rat Foxe1 replaced the endogenous sequence spanning from the start site to the end of the homeobox (nucleotide positions 7957 to 9480). Sv40 pA was added after the stop codon, as well as a PGK-neo cassette. The inserted sequence was ectopically expressed in Titf1 expression domains like the lung and diencephalons, (J:95017)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Insertion
--
1
8
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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