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Sequence coding for the Itgb4 cytoplasmic domain up to amino acid 1355, a stop codon, SV40 pA signal sequences, and a neomycin resistance gene cassette were inserted immediately downstream of the exon encoding the transmembrane segment of the protein. Immunoprecipitation and FACS analysis on primary keratinocytes indicated that the mutant protein is expressed at the cell surface. (J:94627)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
