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This transgene included a 3.6 kb fragment encoding the muring Upk2 gene promoter placed upstream of a 3.0 kb sequence encoding a mutant rabbit Hras gene (glutamine to leucine point mutation at codon 61). Mice carrying this allele produced only a single fragment, 8.2 kb in length, corresponding to a tail to tail orientation. Approximately 2 copies of the transgene were inserted into the genome. (J:69251)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
