The transgene contains the promoter, first intron and 5' untranslated region of the human keratin 18 gene and the 34-bp alpha mosaic virus transcriptional enhancerdriving the expression of a beta-galactosidase gene that contains an SV40 large T antigen nuclear localization signal. X-gal staining analysis indicated that expression occurs in the airway epithelium of transgenic mice. (J:94886)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count