Log In|Sign Up
EN
A targeting construct was used to replace exon 2 with the endogenous 56 bp secretion signal sequence upstream of a hemagglutinin-tagged mature Serpine2 1137 bp cDNA sequence. Downstream of this were IRES-NLS-lacZ-pA and TK-neo-pA cassettes. By staining, expression profiles of Beta-galactosidase in sagittal sections were as expected as activity was under the control of the Serpine2 regulatory sequences. (J:94811)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
