This allele is a derivative of Foxm1tm1Rhc. The region flanked by loxP sites was deleted in the germline by mating mice carrying the floxed allele to mice carrying the Tg(EIIa-cre)C5379Lmgd transgene. Resulting chimeric mice were screened for offspring carrying an allele that was missing exons 4-7. RNase protection assays confirmed that no detectable transcript was expressed from this allele. (J:94883)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129X1/SvJ
Targeted
Intragenic deletion
--
1
--
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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