Log In|Sign Up
EN
This transgene contains the MMTV LTR (mouse mammary tumor virus long terminal repeat) fused to the HPV16 E6 and E7 orf sequences. The polyA tail is from SV40. Mice possessed 4-5 head to tail copies of the transgene. The transgene followed a Mendelian pattern of inheritance. Transgene expression was detected in testicular tumors and the submandibular gland, but not in the lung or the spleen. (J:93826)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
