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Neo-LacZ cassette was inserted into ATG initiation codon to disrupt the coding frame. The targeting vector contains a mutation to change ATG to ATC and a replacement of 203 bp downstream of ATG with the LacZ-Neo resistance cassette. Northern and Western blot analysis confirmed the absence of transcription and translation. (J:112201, J:132079)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
