The targeting vector is designed to place a loxP site upstream of exon 1 and a loxP-flanked neomycin cassette downstream of exon 1. Cre-mediated recombination removed the floxed neo cassette. (J:94537)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count