Log In|Sign Up
EN
This transgene contains a HPV16 fragment (NT79-883) encompassing both the E6 and E7 genes along with promoter, 3' UTR, and polyA sequences from human KRT14. Only E7 was expressed due to the presence of a translation termination linker (ttl) in the N terminal region of the E6 gene. Transgene expression was targeted to epithelial tissues. Mice derived from this founder had 20-21 copies of the transgene. (J:86018)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
