The first exon was flanked with loxP sites via homologous recombination. An upstream FRT-flanked neo resistance cassette was removed by crossing with Tg(ACTFLPe)9205Dym transgenic mice. (J:94514)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count