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A 6 kb region extending from exon 5 into exon 10, including the active serine site in exon 5, was replaced with a neomycin resistance cassette. ES cell clone 1A4 generated the mice reported. RT-PCR and Northern blot analysis confirmed the absence of transcript. (J:94751)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
