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A cDNA encoding the full open reading frame of a Japanese genotype 1b virus, HCV-N was cloned downstream of the promoter-enhancer sequences from the murine Albumin gene. The polyA sequence downstream of the insert was derived from the SV40 virus. The transgene was predicted to encode 10 distinct viral proteins. This allele record was associated with founder FL-N/35, which was the only founder line bred to any significant numbers. Transgene expression was detected in the liver. (J:63590)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
