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A cDNA encoding Grin2b and a neomycin resistance gene was inserted directly 3' of the ATG and thereby replaced the endogenous signal sequence. In situ hybridization of brain sections indicated that Grin2b transcript was present in mutant mice. Western blot also indicated the lack of Grin2c protein, while Grin2b protein was present. (J:94369)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
