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A neomycin resistance cassette was inserted in the intron between exons 5 and 6. In exon 5, a mutation was introduced that changes a D codon to an E codon (D246E); this mutates the RGD integrin binding site in the propeptide to RGE. (J:120085)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
