Exons 12, 13 and 14 flanked by two loxP sites one of which also included with an frt flanked neomycin-resistant (neo) cassette. The frt-flp recombination approach was used to selectively excise the neo cassette. In situ hybridization confirmed the absence of transcription. (J:94338)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count