A floxed construct was inserted such that cre-mediated recombination results in the production of an allele that prematurely terminates, putatively precluding autoproteolytic activity and the associated process in which a cholesterol, involved in cell surface tethering, is attached to glycine 198. (J:94270)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count