An NLS-Cre-PGK-neo cassette was inserted into exon one, deleting most of the exon 1 coding sequence of the endogenous gene, shifting the start codon site 3 bp downstream and placing it in a partially optimized KOZAK consensus sequence. (J:94203)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count