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Crossing Gabbr1tm2Bet with Cre-deleter mice resulted in this allele in which exons 7 and 8 are replaced with a single lox511 site. This region is involved in GABA-binding and the removal of the exons caused a frame shift that prevented translation of the full-length protein. Immunoblot indicated the lack of protein in brain extracts from mutants. (J:94234)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
