A transgene expressing the murine H2-K b class I variant was derived from a 7.5-kb genomic clone. Dormant 150-bp loxP sites were inserted into the Hinc II site 5' of exon 1 and the Bam HI site in intron 3 of the construct. At the 3' end of the construct there is a 74-bp tail containing the 5' end of the HSV-1 thymidine kinase gene. (J:87648)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
NOD
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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