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The floxed promoter and exons 1-6 region and the neo cassette were deleted upon crossing with mice expressing Cre recombinase in the germ line. Immunoblot indicated that levels of protein in heterozygote MEFs were approximately half that of wild-type MEFs. (J:94133)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
