A GFP gene was fused in frame to the first exon. A floxed neo cassette replaced the rest of exon 1, exons 2 and 3, and part of exon 4. The floxed neo cassette was subsequently removed but the GFP gene was not functional. Immunohistochemistry, Western blot analysis, and Northern blot analysis confirm the absence of gene products. (J:94338)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
Insertion, Intragenic deletion
--
1
--
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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